Evaluation of Antispasmodic Activity of Petroleum Ether Extract of Seeds of Apium graveolens Linn(PEESAG) on Acetylcholine Induced Contraction in Guinea Pigs Ileum- An experimental study
نویسندگان
چکیده
Background: Apium graveolens Linn. is one of the oldest medicinal plants which used since ancient time in Unani System of Medicine for the disease of gastrointestinal tract which acts as antispasmodic and carminative activity. The aim of this study was to determine the antispasmodic activity of A. graveolens in Guinea Pigs Ileum against acetylcholine induced contractions. Materials and Methods: Antispasmodic activity of PEESAG at the doses of 100, 200, 500, 600, 800 and 900 mcg/ml against acetylcholine at the dose of 10 mcg/ml in guinea pigs. Results: The test drug produced antispasmodic effect 80%, 90% and 100% at the dose of 600, 800 and 900 mcg/ml respectively. Conclusion: This result suggests that the PEESAG revealed antispasmodic activity.
منابع مشابه
Antispasmodic Activity of Petroleum Ether Extract of Seeds of Apium graveolens (PEESAG) on Histamine Induced Contraction in Guinea Pig’s Ileum
Background: Apium graveolens has been used in Unani system of medicine as anti inflammatory, uricosuric, diuretic, carminative, antidyslipidemic, abdominal discomfort etc.The aim of the present study was to determine the antispasmodic activity of A. graveolens in Guinea Pigs against histamine induced contractions. Materials and Methods: Antispasmodic activity of PEESAG at the doses of 100, 200,...
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